NEJM -- Peginterferon Alfa-2a plus Ribavirin for (Hep C Chronic Fatigue)
NEJM -- Peginterferon Alfa-2a plus Ribavirin for
Peginterferon Alfa-2a plus Ribavirin for
Moving right along, I'll up-date the progression with my
Hep C Related Chronic Fatigue Information
Treating chronic mutational hepatitis B with Chinese medicine Vitalliver (Vigconic suppositories)
ZHANG GUAN HUA, LIANG CHAO, ZHENG WAN PIN
Chengdu University of TCM, Hepatitis Laboratory in the attached hospital of Chengdu University of TCM, Sichuan, China
Research Method:
Quantitative determination by contrasting HBV-DNA of cases before and after the treatment.
Number of cases: 25 (n)
Case Selection: Between the age of 16 and 65, in accordance with the diagnosis standards pf chronic Hepatitis B, with negative e antigen and positive e antibody, HBV-DNA > 1 104 cp/mL.
Detection Method: All the blood samples are detected by Sichuan Clinical Detection Center; PCR-ELISA quantitative determination is used within detection range of 1 104 - 1 107-8, HBV-DNA, unit of measurement is cp/mL.
Direction Plan: one suppository provided by Vigconic (International) Ltd. Bid. The course of treatment is six months, the tracing observation after withdrawal lasts six months.
Observation index:
Criterion of Therapeutic Effect:
HBV-DNA volume 1 104 cp/mL: 2/25 (8%)
Among the results of lasting response, 16 blood serum samples are detected through fluorimetric quantitative determination PCR by the instruments of PE.USD, H-7700 in the second attached hospital of Guangzhou Medical College. The result is in accordance with that in Sichuan Clinical Testing Center. (8 cases among it
Conclusion
The reason for the repeatedly abnormal liver function of Chronic Hepatitis B (CHB) patients lies in the repeatedly duplication of HBV after infection, which leads to fibrosis of liver, then cirrhosis and liver cancer. It is commonly accepted that if CHB shows the transformation of HBeAg/Anti-HBe, HBV-DNA becoming negative, liver function returning to normal state, the disease is relieved. However, parts of patients with the transformation of HBeAg/Anti-HBe still remain positive in HBV-DNA and the pathological change in the liver continues. Because HBV-DNA occurs promoter mutation in the anterior C section (1896 necleoside G-A variation) or in the C section (1762 nucleoside T variation, 1764 G-A variation), HBeAg cannot come into being. Therefore, the HBeAg in the patient s blood cannot be detected, while the virus can keep on duplicating and fixing itself. Through sequential assay of nucleic acid, it proves that promoter mutation appears in 30%-60% of HBeAg negative Chronic Hepatitis B (CHB) in the anterior C section or in the C section. In some provinces and cities of the People of China, the percentage of promoter mutation appears in HBeAg negative Chronic Hepatitis B (CHB) in the anterior C section or in the C section is from 17.6% to 78.9%. Eight out of the 25 cases of our observation go through the sequential assay of nucleic acid carried out by the Department of Microbiology of the University of Hong Kong. It all proves to have HBV-DNA mutation. The chronic mutational Hepatitis B is infectious and apt to cause cirrhosis and liver cancer since the present medicines of antivirus and immuno-modulator do not produce the expected therapeutic effects.
Vitalliver suppository is made up from a formula of Chinese herbs, including Ginseng, Deer Horn, Cordyceps, Radix Astragali, Frudctus Cnidii, Semen Cuscutae, etc. The formula is mainly for strengthening the body resistant and primarily for reinforcing Kidney Qi, which produces good therapeutic effects in treating chronic mutational Hepatitis B. The mechanism is probably that through the regulating of immune system, the duplication of virus is inhibited and meanwhile the liver is protected, so it can produce a lasting therapeutic effect. No adverse reaction and severe accident happens during clinical observation, so it is safe for using. Vitalliver is bringing hopes to the treatment of chronic mutational Hepatitis B.
* The second stage of clinical trial would be carrying out by the Microbiology Department of the University of Hong Kong and Chengdu University of Traditional Chinese Medicine.
For more information, please visit: http://www.vigconic.com
Or, contact:
William Yip cs@vigconic.com
5/F, Cheung Wah Building, Sheung Heung Rd,
Kowloon, Hong Kong
Tel: 852-27656200
Fax: 852-27645314
Chengdu University of TCM, Hepatitis Laboratory in the attached hospital of Chengdu University of TCM, Sichuan, China
Sharing needles, straws, pipes, spoons and other drug-related equipment.
(At least two-thirds of all new hepatitis C infections are drug-use related. Cleaning equipment with bleach does not always effectively kill the virus)
Getting a tattoo, body piercing or acupuncture from an operator who does not use sterile equipment or techniques
Being born to a mother with hepatitis C
Getting pierced by a needle or sharp equipment that has infected blood on it ( in a hospital, workplace situation, etc.)
People who had blood transfusions before the testing of blood donations became mandatory in 1990 may also be at risk. And, while the risk is low, it is also possible to become infected by sharing personal household articles such as a razor or toothbrush with an infected person. The risk of transmission of hepatitis C during sex is also low, unless both parties have open bleeding sores.
It is estimated that 240, 000 people in Canada are currently infected with hepatitis C, of whom only 30% know they have the virus.
If you think you may be at risk, either now or from past risky activities see a doctor. The virus can be detected with a simple blood test, and there are steps and medications you can take to successfully minimize the effects of the disease if your diagnosis is positive. For more information, visit Health Canada's Web site at www.healthcanada.ca/hepc.
About The Author
News Canada provides a wide selection of current, ready-to-use copyright free news stories and ideas for Television, Print, Radio, and the Web.
News Canada is a niche service in public relations, offering access to print, radio, television, and now the Internet media, with ready-to-use, editorial "fill" items. Monitoring and analysis are two more of our primary services. The service supplies access to the national media for marketers in the private, the public, and the not-for-profit sectors. Your corporate and product news, consumer tips and information are packaged in a variety of ready-to-use formats and are made available to every Canadian media organization including weekly and daily newspapers, cable and commercial television stations, radio stations, as well as the Web sites Canadians visit most often. Visit News Canada and learn more about the NC services.
Treating chronic mutational hepatitis B with Chinese medicine Vitalliver (Vigconic suppositories)
ZHANG GUAN HUA, LIANG CHAO, ZHENG WAN PIN
Chengdu University of TCM, Hepatitis Laboratory in the attached hospital of Chengdu University of TCM, Sichuan, China
Research Method:
Quantitative determination by contrasting HBV-DNA of cases before and after the treatment.
Number of cases: 25 (n)
Case Selection: Between the age of 16 and 65, in accordance with the diagnosis standards pf chronic Hepatitis B, with negative e antigen and positive e antibody, HBV-DNA > 1 104 cp/mL.
Detection Method: All the blood samples are detected by Sichuan Clinical Detection Center; PCR-ELISA quantitative determination is used within detection range of 1 104 - 1 107-8, HBV-DNA, unit of measurement is cp/mL.
Direction Plan: one suppository provided by Vigconic (International) Ltd. Bid. The course of treatment is six months, the tracing observation after withdrawal lasts six months.
Observation index:
Criterion of Therapeutic Effect:
HBV-DNA volume 1 104 cp/mL: 2/25 (8%)
Among the results of lasting response, 16 blood serum samples are detected through fluorimetric quantitative determination PCR by the instruments of PE.USD, H-7700 in the second attached hospital of Guangzhou Medical College. The result is in accordance with that in Sichuan Clinical Testing Center. (8 cases among it
Conclusion
The reason for the repeatedly abnormal liver function of Chronic Hepatitis B (CHB) patients lies in the repeatedly duplication of HBV after infection, which leads to fibrosis of liver, then cirrhosis and liver cancer. It is commonly accepted that if CHB shows the transformation of HBeAg/Anti-HBe, HBV-DNA becoming negative, liver function returning to normal state, the disease is relieved. However, parts of patients with the transformation of HBeAg/Anti-HBe still remain positive in HBV-DNA and the pathological change in the liver continues. Because HBV-DNA occurs promoter mutation in the anterior C section (1896 necleoside G-A variation) or in the C section (1762 nucleoside T variation, 1764 G-A variation), HBeAg cannot come into being. Therefore, the HBeAg in the patient s blood cannot be detected, while the virus can keep on duplicating and fixing itself. Through sequential assay of nucleic acid, it proves that promoter mutation appears in 30%-60% of HBeAg negative Chronic Hepatitis B (CHB) in the anterior C section or in the C section. In some provinces and cities of the People of China, the percentage of promoter mutation appears in HBeAg negative Chronic Hepatitis B (CHB) in the anterior C section or in the C section is from 17.6% to 78.9%. Eight out of the 25 cases of our observation go through the sequential assay of nucleic acid carried out by the Department of Microbiology of the University of Hong Kong. It all proves to have HBV-DNA mutation. The chronic mutational Hepatitis B is infectious and apt to cause cirrhosis and liver cancer since the present medicines of antivirus and immuno-modulator do not produce the expected therapeutic effects.
Vitalliver suppository is made up from a formula of Chinese herbs, including Ginseng, Deer Horn, Cordyceps, Radix Astragali, Frudctus Cnidii, Semen Cuscutae, etc. The formula is mainly for strengthening the body resistant and primarily for reinforcing Kidney Qi, which produces good therapeutic effects in treating chronic mutational Hepatitis B. The mechanism is probably that through the regulating of immune system, the duplication of virus is inhibited and meanwhile the liver is protected, so it can produce a lasting therapeutic effect. No adverse reaction and severe accident happens during clinical observation, so it is safe for using. Vitalliver is bringing hopes to the treatment of chronic mutational Hepatitis B.
* The second stage of clinical trial would be carrying out by the Microbiology Department of the University of Hong Kong and Chengdu University of Traditional Chinese Medicine.
For more information, please visit: http://www.vigconic.com
Or, contact:
William Yip cs@vigconic.com
5/F, Cheung Wah Building, Sheung Heung Rd,
Kowloon, Hong Kong
Tel: 852-27656200
Fax: 852-27645314
Chengdu University of TCM, Hepatitis Laboratory in the attached hospital of Chengdu University of TCM, Sichuan, China
Sharing needles, straws, pipes, spoons and other drug-related equipment.
(At least two-thirds of all new hepatitis C infections are drug-use related. Cleaning equipment with bleach does not always effectively kill the virus)
Getting a tattoo, body piercing or acupuncture from an operator who does not use sterile equipment or techniques
Being born to a mother with hepatitis C
Getting pierced by a needle or sharp equipment that has infected blood on it ( in a hospital, workplace situation, etc.)
People who had blood transfusions before the testing of blood donations became mandatory in 1990 may also be at risk. And, while the risk is low, it is also possible to become infected by sharing personal household articles such as a razor or toothbrush with an infected person. The risk of transmission of hepatitis C during sex is also low, unless both parties have open bleeding sores.
It is estimated that 240, 000 people in Canada are currently infected with hepatitis C, of whom only 30% know they have the virus.
If you think you may be at risk, either now or from past risky activities see a doctor. The virus can be detected with a simple blood test, and there are steps and medications you can take to successfully minimize the effects of the disease if your diagnosis is positive. For more information, visit Health Canada's Web site at www.healthcanada.ca/hepc.
About The Author
News Canada provides a wide selection of current, ready-to-use copyright free news stories and ideas for Television, Print, Radio, and the Web.
News Canada is a niche service in public relations, offering access to print, radio, television, and now the Internet media, with ready-to-use, editorial "fill" items. Monitoring and analysis are two more of our primary services. The service supplies access to the national media for marketers in the private, the public, and the not-for-profit sectors. Your corporate and product news, consumer tips and information are packaged in a variety of ready-to-use formats and are made available to every Canadian media organization including weekly and daily newspapers, cable and commercial television stations, radio stations, as well as the Web sites Canadians visit most often. Visit News Canada and learn more about the NC services.